Abstract
Concentrations of chloramphenicol and penicillin G which permit growth induce the formation of temporary filaments, morphologically and ultrastructurally identical to stable, chemically-induced filamentous mutants ofAgmenellum quadruplicatum strainBG-1. These induced filaments were propagated by serial transfers in the presence of inhibitor and underwent an immediate, synchronous reversion upon its removal. The reversion of penicillin-induced filaments was insensitive to inhibitors of DNA synthesis but sensitive to inhibitors of protein synthesis until the completion of the mucopolymer septum. Penicillin G blocked the early stages or initiation of cell division. Chloramphenicol blocked the terminal stages of cell division, the cleavage of the mucopolymer septum by the outer wall layers.
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