Effects of Schisandra Polysaccharides on the Learning and Memory Ability in Brain Aging Mice

Abstract

This study focused on the improvement of Schisandra polysaccharide on the learning and memory in D-galactose-induced brain aging mice, to lay the foundation for the prevention and treatment of brain aging and related diseases. D-galactose was used to establish a mice brain aging model, Morris water maze and passive avoidance test were used to observe effects of Schisandra polysaccharide on the learning and memory ability of D- galactose-induced brain aging mice. The results showed that Schisandra polysaccharide could prolong the time of target qundrant, increase the number to cross the original platform in the Morris water maze test, and prolong the latency and reduce the number of errors of mice in the passive avoidance test. It is believed that Schisandra polysaccharide could improve the learning and memory ability of mice with brain aging.