Effects of Salivary Oxidative Markers on Edentulous Patients' Satisfaction with Prosthetic Denture Treatments: A Pilot Study.

Chia-Huang Chang,Sheng-Wei Feng,Chang-Yu Lee,Nae-Fang Miao,Pei-Huan Lin,Yung-Kai Huang,Che-Tong Lin,Shin-Han Tsai,Gururaj Arakeri

doi:10.1371/journal.pone.0151605

Chia-Huang Chang, Sheng-Wei Feng + Show 7 more

Open Access

https://doi.org/10.1371/journal.pone.0151605

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Abstract

ObjectivesThe purpose of this study was to assess relationships among periodontal conditions, salivary antioxidant levels, and patients’ satisfaction with their prostheses.MethodsThis study was conducted at the Division of Prosthodontics, Department of Dentistry, Taipei Medical University Hospital. The periodontal condition of patients was based on an assessment of the plaque index (PI) and gingival index (GI). The pH value, flow rate, and buffer capacity of the saliva were estimated. The salivary total antioxidant status (TAS) and superoxide dismutase (SOD) level were also determined. Patients’ satisfaction with prosthetic treatments was evaluated using the Chinese version of the short-form Oral Health Impact Profile (OHIP-14C). A multivariate regression model was used to determine whether patients’ satisfaction with prosthetic treatment was affected by their oral health status.ResultsIn total, 35 edentulous patients were recruited. In the Spearman correlation analysis, salivary pH (r = -0.36, p = 0.03) and the buffer ability (r = -0.48, p<0.01) were associated with OHIP-14C scores. In the multivariate analysis, patients who had a higher GI also had a higher score of physical disabilities (β = 1.38, p = 0.04). Levels of SOD increased with the scores of psychological discomfort (β = 0.33 U/g protein, p = 0.04).ConclusionsThis study suggested that both the GI and SOD levels were associated with patients’ satisfaction with prosthetic treatments. To the best of our knowledge, this is the first study to elucidate the relationship between OHIP scores and salivary oxidative markers in edentulous patients.

Highlights

With increasing life expectancies, aged populations in developing countries are increasing year by year
Patients who had a higher gingival index (GI) had a higher score of physical disabilities (β = 1.38, p = 0.04)
Levels of superoxide dismutase (SOD) increased with the scores of psychological discomfort (β = 0.33 U/g protein, p = 0.04)

Summary

Introduction

With increasing life expectancies, aged populations in developing countries are increasing year by year. Partial and complete edentulism can lead to impaired masticatory function, an unhealthy diet, social disability, and a poor health-related quality of life (QoL, HRQoL) [2]. The oral HRQoL (OHRQoL) is a multidimensional concept with comprehensive evaluations of oral health and function, social and emotional well-being, environment, and treatment expectations [6, 7]. OHRQoL measures were developed and are applied in the clinical practice of dentistry and dental treatments. The OHIP is applied to determine the treatment efficacy, patient satisfaction, dental esthetics, and prosthetic rehabilitation and was translated and adopted in many countries [11,12,13,14]

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