Effects of rotating electric fields on blood metabolic indicators: an experimental study

Abstract

BACKGROUND: Stress is an integral part of life in both humans and animals. Up to 70% of the Russian population have reported a certain degree of stress associated with approximately 80% of diseases. This heavy burden of stress explains a significant body of research on the issue of stress and its associations with health indicators. AIM: To study the effects of rotating electric fields on blood metabolic parameters in experimental animals with different levels of resistance to stress. MATERIALS AND METHODS: A total of 54 non-inbred white male rats comprised the sample. We measured serum levels of 11-hydroxycorticosteroids, glucose, C-reactive protein, total sialic acids and the activity of hepatospecific enzymes, such as aspartate transferase, alanine transferase, and alkaline phosphatase at the 10th and the 20th day of exposure to a man-made rotating electric field and in the non-exposed control group. By the level of resistance to stress all rats were divided into stress-resistant, stress-unresistant and ambivalent groups using the "open field" method. RESULTS: On the 10th day of exposure, the levels of 11-hydroxycorticosteroids, glucose, C-reactive protein, total sialic acids increased in all three groups of animals. The activity of aspartate transferase, alanine transferase, and alkaline phosphatase also increased in all rats. On the 20th day, the studied parameters remained elevated compared to the control group. The most pronounced changes were observed in the group of stress-unresistant individuals. CONCLUSION: Our results demonstrate significant effects of rotating electric fields on blood metabolic indicators in rats. The degree of change depends on individual level of stress resistance.