Effects of real-time shear wave elastography combined with color Doppler ultrasound in the differential diagnosis of benign and malignant breast lesions

Abstract

Objective To observe the clinical effects of real-time shear wave elastography (SWE) combined with color Doppler ultrasound in the differential diagnosis of benign and malignant breast lesions. Methods A total of 104 cases (115 lesions) of breast masses treated in Yangquan First People’s Hospital from November 2017 to October 2018 were selected, and pathological results were obtained through puncture biopsy or surgical resection. The selected patients were examined by color Doppler ultrasound and SWE. The diagnostic accuracy, specificity and sensitivity of color Doppler ultrasound, SWE and color doppler ultrasound + SWE were evaluated, with pathological results as the gold standard. Results Among the 115 breast masses, 50 cases were benign and 65 cases were malignant. Among the 115 breast masses diagnosed by color Doppler ultrasound, 51 cases were benign and 64 cases were malignant. SWE checked out 53 cases of benign and 62 cases of malignant; color Doppler ultrasound + SWE diagnosed 49 cases of benign and 66 cases of malignant. The accuracy, specificity and sensitivity of ultrasonography in the diagnosis of breast lesions were 78.26%, 76.00% and 80.00%, respectively. The accuracy, specificity and sensitivity of SWE in the diagnosis of breast lesions were 86.96%, 88.00% and 86.15%, respectively. The accuracy, specificity and sensitivity of ultrasonography + SWE in the diagnosis of breast lesions were 95.65%, 94.00% and 96.92%, respectively. The accuracy, specificity and sensitivity of ultrasonography plus SWE in the diagnosis of breast lesions were higher than that of ultrasonography or SWE, and the difference was statistically significant (P<0.05). Conclusions The combined use of SWE and color Doppler ultrasonography in the differential diagnosis of benign and malignant breast lesions is effective, which is helpful to improve the detection rate of breast cancer and provide guidance for clinical treatment. Key words: Benign and malignant breast lesions; Real-time shear wave elastography; Color Doppler ultrasound; Diagnostic accuracy