Abstract

The present study was designed to investigate the effects of Plantago major L. seeds extract (PE) on endurance exercise capacity in mice. Forty eight male mice were randomly divided into four groups, such as control, low-dose PE treated, middle-dose PE treated and high-dose PE treated. The mice in the treated group were received PE (30, 60 and 120 mg/kg, i.g), and the mice in the control group received drinking water i.g for 4 weeks. The results showed that PE prolonged the swimming time as well as glycogen amount in mice, but decrease serum urea nitrogen and blood lactate. These data suggest that PE improved endurance exercise capacity and possessed anti-fatigue effect. PE may be useful for the development of physical strength. Key words: Plantago major L., seeds extract, endurance exercise capacity, mice, anti-fatigue effect.

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