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Abstract
Physiological changes are described following exposure of mice to single and intermittent noise stimulation (110 db re 0.0002 dyne/cm2, 10–20 kc) for varying lengths of time. Attention is focused on the degree of adreno-cortical activation as measured by cytological changes in the adrenal gland and fall in the number of circulating eosinophils. Since the observed changes were transient, of short duration and no evidence of systemic pathology could be detected, the noise was described as not harmful. The tendency of certain investigators to regard noise as an injurious, nonspecific stress stimulus without specifying the exact nature of the noise situation does not seem justified.
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