Abstract
Probiotic sour beer (PRO) fermented with Lacticaseibacillus paracasei Lpc-37 is a novel beverage option, which may potentially offer health benefits. In this study, the effects of PRO are evaluated on the inflammatory, immunity, lipid profile, and gut microbiome of consumers in a 5-week, participant-blinded, randomized-controlled within-subject crossover study. Twenty-one healthy male participants consumed 330 mL of PRO and normal sour beer (CON) daily for 2 weeks each with a 1 week of washout. Stool and blood samples were collected before and after each intervention. Significant increases for Proteobacteria and Bacteroides and a significant decrease in Dialister (p < 0.05) were observed in the CON group, while gut microbiome populations remained relatively stable in the PRO group. A significant increase was also found in HDL-cholesterol after PRO (p < 0.05), while no significant differences were observed in inflammatory and immunity profiles. Further research is warranted to explore its HDL-cholesterol increasing potential.
Published Version
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