Abstract
Objective: The current treatment strategy for endometriosis includes the long-term medical suppression after surgery to prevent the recurrence of symptoms and lesions. Several studies have demonstrated the efficacy, safety and tolerability of dienogest (DNG) for the treatment of endometriosis. As DNG inhibits ovulation, there could be concern about its negative effect on bone health, especially with long-term use. This study was performed to evaluate the effects of long-term postoperative use of DNG on bone mineral density (BMD) in patients with ovarian endometrioma.
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