Effects of long-term prophylaxis with bromhexine hydrochloride and treatment with high colchicine doses of COVID-19

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In a series of publications, we attempt to demonstrate the prophylactic role of bromhexine hydrochloride (BHH) and the curative role of high colchicine doses against COVID-19. Effects of long-term prophylaxis with BHH are present with two cases of elderly women with severe comorbidity. After long-term prophylactic use of BHH from 3 to 6 months, one did not fall sick from COVID-19 and the other passes it almost asymptomatically, even though all their family members fell ill. The dramatic healing effect of colchicine was demonstrated in a family in which both spouses became ill with COVID-19 almost simultaneously. They are treated in different hospitals, and where colchicine is administered in high doses, the patient recovered. The other patient developed complications and died on standard treatment without high doses of colchicine. An outpatient accidentally overdosed with colchicine (12.5mg). The therapy was stopped immediately. Clinically, on the third day, there are absolutely no symptoms. These cases re-affirm the prophylactic effect of BRH and the curative effect of high-dose colchicine.