Abstract
Objective To explore the effects of heated humidified high flow nasal cannulae (HFNC) oxygen therapy among patients with pulmonary fibrosis. Methods A total of 60 patients in accord with diagnostics guide for idiopathic pulmonary fibrosis and admitted to Department of Respiratory at a Class III Grade A hospital in Tianjin for pulmonary fibrosis were selected by convenience sampling from May 2016 to March 2017. They received oxygen inhalation through nasal cannula for 24 hours and sequentially HFNC oxygen therapy for 24 hours respectively. The blood gas analysis, degree of comfort, severity of dyspnea and incidence of complications were compared two, four and twenty-four hours after adopting oxygen inhalation through nasal cannula and HFNC oxygen therapy. Results There were statistically significant differences in PaO2, SpO2, base excess (BE) and respiratory rate (RR) between oxygen inhalation through nasal cannula and HFNC oxygen therapy (P 0.05) . Conclusions The application of HFNC can increase PaO2 and SpO2, and slow RR among patients with pulmonary fibrosis. Meanwhile, it can also effectively improve the severity of dyspnea, promote patients′ comfort and reduce the incidence of complications. Key words: Humidification oxygen therapy with high flow capacity; Pulmonary fibrosis
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