Abstract
This chapter presents the effects of high-voltage prickle electrostatic field (HVPEF) on the expressions of the surface molecules on the T Lymphocytes and antigen presenting cells (APCs) of mice. Kunming mice are selected and randomly grouped. Whole body treatment of HVPEF is performed. Flow cytometry (FCM) is adopted to detect the expression changes of surface molecules after different doses of HVPEF by dose-effect and time-course studies. The dose-effect results show the opposite directions of the surface molecule expressions after HVPEF. The time-course results show that the peak of expressions appeared at about 8-16h after 15kv HVPEF (P<0.001) and then recovered gradually. 24h saw the recovery to the baseline. The expressions decrease beginning from 2h and rapidly reaching their minimums after 35kv HVPEF, the lower level of expressions maintained up to 24h. The different doses of HVPEF might cause different changes of the surface molecule expressions on T lymphocytes and APCs, which suggests that HVPEF has potential immune-regulatory effects and changes of expressions might play important roles in immune modulation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
