Effects of feeding metabolite combinations from lactobacillus plantarum on plasma and breast meat lipids in Broiler Chickens

Tc Loh,Nt Thanh,Hl Foo,M Hair-Bejo

doi:10.1590/s1516-635x2013000400004

Abstract

The effects of feeding different doses of metabolite combination of L. plantarum RS5, RI11, RG14 and RG11 strains (Com3456) on cholesterol reduction in plasma and breast meat in broiler chickens and the possible mechanism was studied. A total of 504 male Ross broilers were grouped into 7 treatments and offered with different diets: (i) standard corn-soybean based diet (-ve control); (ii) standard cornsoybean based diet + neomycin and oxytetracycline (+ve control); (iii) standard corn-soybean based diet + 0.1% metabolite combination of L. plantarum RS5, RI11, RG14 and RG11 strains (Com3456); (iv) standard corn-soybean based diet + 0.2% of Com3456; (v) standard cornsoybean based diet + 0.3% of Com3456 (vi) standard corn-soybean based diet + 0.4% of Com3456 and (vii) standard corn-soybean based diet + 0.5% of Com3456. The metabolite combinations supplemented in the diet of broilers reduced protein, cholesterol esters concentration in very low-density lipoprotein particles. The present of organic acids and proteinaceous compound in the metabolite combinations as found in previous study also increased lactic acid bacteria count in small intestine digesta and improved bile salts deconjugation ability of lactic acid bacteria.

Highlights

Metabolites produced by lactic acid bacteria are known for their antibacterial substances, such as organic acids and proteinaceous compounds (Thu et al, 2011a), and broader application in food industries
It has been shown that there is a reduction of plasma cholesterol concentration in rats supplemented with the metabolite (Foo et al, 2003a; Loh et al, 2008)
The highest (p < 0.05) breast meat cholesterol was observed in broiler chickens fed the -ve control diet, followed by group supplemented with 0.1% Com3456, while no significant difference (p > 0.05) was found for the remaining treatments

Summary

Introduction

Metabolites produced by lactic acid bacteria are known for their antibacterial substances, such as organic acids and proteinaceous compounds (Thu et al, 2011a), and broader application in food industries. These metabolites have attracted attention to be applied in animal feed as growth promoter and potentially used as substitution of in-feed antibiotics (Thanh et al, 2009; Loh et al, 2010; Thu et al, 2010; Thu et al, 2011b, Choe et al, 2012). The effect of feeding metabolites to broiler chickens on blood lipids and the mechanisms involved are still unclear It is believed very low-density lipoproteins (VLDL) play important roles in regulating the cholesterol concentration in the body of broiler chickens. VLDL is known to transport the lipids synthesized in the liver to extrahepatic tissues, such as adipose tissue, muscle, heart, etc. (Devlin, 2002)

Methods

Results

Conclusion