Abstract

The cerebral venous outflow of monkeys (baboons) was monitored by means of electromagnetic flow probes before, during, and after the intravenous injection of Hydergine. Cerebral blood flow (CBF), cerebral vascular resistance (CVR), arteriovenous oxygen differences, cerebral oxygen consumption (CMRO 2), arterial blood pressure (MABP), end-tidal CO 2, and the EEG were also monitored. Hydergine in doses of 0.06 mg/kg body weight produced statistically-significant but short-lasting increases in CBF and CMRO 2 accompanied by decreases in CVR and MABP. There were no changes in the EEG.

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