Effects of Duragesic on the treatment of moderate or severe pain caused by cancer and the nursing of its adverse effects

Abstract

Objective To study the clinical effects and feasibility of nursing intervention for adverse effects of Duragesic when it prevented moderate or severe cancer pain. Methods A total of 192 patients, who had acquired moderate or serious cancer pain in our hospital during December 2011 and December 2013, had been chosen as objectives and divided into observation group (nursing intervention model) and control group (routine nursing) on average. The analgesic effect and adverse effects of patients were compared between two groups. Results Compared the results of pain relief, the effective rate of pain relief at sixth and ninth day of treatment were 44.79% (43/96) and 66.67% (64/96) higher than 22.92% (22/96) and 44.79% (43/96) of the control group (χ2=10.267, 9.310; P 0.05). Compared the adverse effect in two groups, the incidences of vomiting, nausea, constipation and dysuria in the control group were higher than these of the observation group (χ2=5.603, 5.438, 4.364, 3.544; P 0.05). Conclusions The nursing intervention model had apparent effect on preventing adverse effects of patients with moderate or serious cancer pain treating with Duragesic. It could effectively improve psychological status of patients and life quality, and be helpful to restore their health. Key words: Nursing intervention; Moderate or severe cancer pain; Adverse effects; Duragesic