Effects of different blood pressure control levels on rebleeding and prognosis of patients with hypertensive cerebral hemorrhage

Abstract

Objective To explore the effect of different blood pressure control levels on the risk and prognosis of rebleeding in patients with hypertensive cerebral hemorrhage (<30 mL). Methods Two hundred and forty-five patients who met the inclusion criteria in the Department of Neurosurgery, Liangping District People’s Hospital from July 2015 to July 2018 were randomly divided into two groups by date. In acute phase, intravenous drugs were mainly used, oral antihypertensive drugs were mainly used after blood pressure was stable, and intravenous antihypertensive drugs were supplemented. The blood pressure of 120 patients in the control group was controlled at 140/80-160/100 mmHg (1 mmHg= 0.133 kPa), and that of 125 patients in the experimental group was controlled below 140/80 mmHg. The clinical data of the two groups were analyzed, and the incidence of rebleeding, cerebral perfusion pressure, clinical neurological deficit score (FD), total living ability status (BI) and prognosis of the two groups were compared, as well as the relationship between rebleeding and prognosis. Results There was no significant difference between the two groups in terms of general data (P>0.05); the risk of rebleeding in the experimental group was lower than that in the control group (P 0.05); there was no significant difference between the two groups in the indexes of FD and BI at 3, 10, 30 d and 6 months after the onset of the disease (P>0.05); half a year after the onset of rebleeding patients were followed up and found that the experimental group recovered better than the control group. Conclusion Blood pressure control below 140/80 mmHg reduced the risk of rebleeding and improved the prognosis of rebleeding patients. Key words: Hypertensive cerebral hemorrhage; Blood pressure; Rebleeding; Prognosis