EFFECTS OF DIETARY SODIUM MONENSIN ON THE METABOLIC AND HORMONAL PROFILES OF DAIRY GOATS DURING THE PERIPARTUM PERIOD

Cleyber José Trindade De Fátima,Adony Querubino De Andrade Neto,Carla Lopes De Mendonça,Sergio Peres Ramos Da Silva,José Augusto Bastos Afonso,Adalberto Freire Do Nascimento Júnior

doi:10.1590/1809-6891v19e-51453

Cleyber José Trindade De Fátima, Adony Querubino De Andrade Neto + Show 4 more

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https://doi.org/10.1590/1809-6891v19e-51453

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Abstract

Abstract This study aimed to investigate the energetic and hormonal profiles of dairy goats fed diets supplemented with monensin during the peripartum period. Eleven pregnant Saanen goats were subdivided into two random groups, a control group (GC) and the monensin group (MG). The MG group received 40 mg sodium monensin per animal per day for 15 days before partum and throughout the subsequent experimental period. Clinical observations and sample collection were performed at 30, 15, and 7 days before birth; on the day of partum; and at 5, 15, and 30 days after birth. The following biochemical and hormonal profile variables analyzed were: cholesterol, triglycerides, glucose, fructosamine, non-esterified fatty acids (NEFAs) and β-hydroxybutyrate (BHB), cortisol, and insulin. The ruminal fluid pH, chloride content, and volatile fatty acids were also measured. Statistical analysis of the data was performed using repeated measures ANOVA (p < 0.05) and Pearson's correlation. At partum, the MG group had lower values of NEFAs and lower acetate/propionate ratio. MG had higher triglycerides during the entire experiment period. The administration of monensin generated benefits in terms of energy parameters, improving the metabolic status of the dairy goats during peripartum.

Highlights

The transition period in goats includes three weeks before and after calving and is considered critical in view of the intense metabolic changes and adaptations to a new physiological state
This study aimed to investigate the energetic and hormonal profiles of dairy goats fed diets supplemented with monensin during the peripartum period
There were no significant differences between the control group (CG) and monensin group (MG) groups in terms of the volatile fatty acids (VFAs) analyzed (p > 0,05)

Summary

Introduction

The transition period in goats includes three weeks before and after calving and is considered critical in view of the intense metabolic changes and adaptations to a new physiological state In this period, losses may occur under conditions of negative energy balance between nutrient demand and adequate supply, resulting from the high nutritional requirement caused by the rapid development of the fetuses and the mammary gland, in addition to a reduced food intake during this period. Monensin sodium has been extensively used to control coccidiosis and improve feed efficiency in ruminants As an ionophore, it modifies the flow of monovalent ions through the cell membrane, altering the profile of the microbial population in the rumen. The consequences of these changes directly influence the metabolic pathway of gluconeogenesis[2,3]

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