Effects of diabetes mellitus types II on salivary flow rate and some salivary parameters (total protein, glucose, and amylase) in Erbil city

Abstract

The concentration of some components of saliva may be associated with certain systemic illnesses, reflecting the hormonal, immunological, neurological, emotional, nutritional and metabolic states of the patient. The aim of this work was to assess salivary flow rate, and to evaluate saliva samples for levels of salivary total protein, glucose, and alpha amylase, in diabetics type II and healthy subject in both genders. Subjects and methods: Unstimulated salivary flow rate, salivary total protein, glucose, and amylase were measured in 90 subjects, 60 with diabetes mellitus type II (30 controlled and 30 uncontrolled diabetic patients) and in 30 healthy subjects. Results: Significant difference in salivary flow rate in diabetic patient when compared with healthy subject. The finding showed no significant differences between salivary total proteins in all groups. Significant difference in salivary glucose and amylase concentration was found between the healthy subjects and type 2 diabetic patients. According to the gender, there were only significant differences between male and female in salivary flow rate for healthy subjects Conclusions: Patients with type 2 diabetes mellitus have higher concentration of salivary glucose and lower value of salivary flow rate and amylase. No significant difference was seen in protein value in all groups. Key wards: Diabetes mellitus , healthy subject, salivary total protein, amylase, glucose. (J Bagh Coll Dentistry 2012;