Effects of combined aerobic and resistant exercise on coronary heart disease patients with type 2 diabetes millitus

Abstract

Objective To explore the effects of individual aerobic combined with resistance training on the blood glucose, blood lipid and total exercise capacity compared with simple aerobic training in the coronary artery disease(CAD)patients with type 2 diabetes mellitus(T2DM)and the possible mechanisms. Methods The total 60 patients of CAD and T2DM were randomly assigned to control group(n=20), aerobic training group(n=20)and combined training group(n=20). Three groups all adopted the routine medication management, health education and diet guide.The control group had no other intervention.The aerobic training group had some 60%-85% of target heart rate(HR)aerobic exercises which was set according to the cardiopulmonary exercise test(CPET). The combined training group adopted isokinetic muscle strength training based on the aerobic training group which set intensity in 11-13 according the RPE.All patients were evaluated with fasting blood-glucose(FBG), glycosylated hemoglobin(HBA1c), total cholesterol(TC), triglyceride(TG), low density lipoprotein(LDL), fat mass(FM), lean body mass(LBM), VO2max, lower limbs peak torque(PT)and balance ability before and after training.Each exercise time 30-60 min, 3 times a week, a total of 12 weeks. Results There was no significant difference among the physiology index in three groups before training(P>0.05). Aerobic training group and combined training group significantly improved compared with control group in blood glucose, blood lipid, FM, VO2max after training(P 0.05). Combined training group had great improvement in lower limbs peak torque and balance ability than the other two groups(P<0.05). Conclusions Individualized aerobic combined with resistance training can give better control of coronary risk factors in CAD-T2DM patients, and improve the muscle strength and balance ability. Key words: Coronary artery disease; Diabetes mellitus; Aerobic training; Resistance training