Abstract
1. 1. Neuron Rl 5 of Aplysia produces a large unitary synaptic potential (EPSP) which may be facilitated to 250 per cent of control amplitude by repeated stimulation. 2. 2. Facilitation is pronounced at 0.5, 1 and 2 Hz but not seen at 0.1 Hz. 3. 3. The amplitude of an unfacilitated EPSP increased in high calcium or low magnesium and decreased in low calcium or high magnesium. Calcium is a stronger regulator than magnesium. 4. 4. The facilitation ratio was greater for initially small EPSP's than for initially large ones. This inverse relationship held in normal and experimental calcium and magnesium concentrations. This relationship could be explained by the superposition of facilitation and depression processes.
Published Version
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