Abstract
The scientific study of individuals with lesions to different brain regions provides important insight into the neurocognitive basis of human spatial navigation. This article describes the lesion-deficit approach to understanding spatial memory and navigation. We begin with an overview of factors that influence navigation, followed by a description of the common causes of selective lesions that are known to affect spatial memory and navigation. We elucidate the distinct roles of key brain regions in different aspects of human spatial memory and navigation, citing examples of individual cases with focal lesions. These regions work within a spatial navigation network in the context of other cognitive processes.
Published Version
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