Abstract
The goal of this study was to examine the effects of α-chloralose and pentobarbital on the somatosensory responses of medullary raphespinal neurons. With α-chloralose, 98% of neurons responded to innocuous stimuli, particularly tapping, but only 1 64 responded selectively to nociceptive stimuli. In contrast, 73% of neurons responded selectively to noxious stimuli with pentobarbital, and none responded selectively to innocuous stimuli. In addition, raphespinal neurons studied with pentobarbital had higher spontaneous discharge rates, and a higher incidence of spontaneity, than neurons studied with α-chloralose. Thus, different anesthetics produce raphespinal neurons with different somatosensory response characteristics.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call