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Abstract
Aim: The present research aims to study the effects of Ancylostoma ceylanicum infection on lactate dehydrogenase activity in the tissues of Mesocricetus auratus. Methodology: In the current investigation, Ancylostoma ceylanicum, a hookworm was infected in the host, a hamster Mesocricetus auratus experimentally in laboratory conditions in Hyderabad from 1992 to 1996. The infected host was then studied using the parameters of Lactate dehydrogenase activity in various tissues. The Lactate Dehydrogenase content in M. auratus was investigated biochemically in both the infected and control samples. Results: The results revealed increased levels of Lactate dehydrogenase in the intestinal and muscle tissue of the infected host. Decreased LDH content in the liver, kidney, spleen, lungs, brain and serum was found in the infected host of Lactate Dehydrogenase as the anaerobic conditions prevail in the intestinal region of the host infected with hookworm infection. Conclusion: The present paper reveals the Lactate dehydrogenase content in Mesocricetus auratus infected with Ancylostoma ceylanicum as compared to control and its significance.
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