Effects of all tram retinoic acid on CD106 and CD54 expression in human bone marrow mesenchymal stem cells in vitro

Junling Tang ,Xiaoming Li

doi:10.3760/cma.j.issn.1009-9921.2008.03.001

Effects of all tram retinoic acid on CD106 and CD54 expression in human bone marrow mesenchymal stem cells in vitro

Junling Tang , Xiaoming Li

https://doi.org/10.3760/cma.j.issn.1009-9921.2008.03.001

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Publication Date: Jun 25, 2008

Affiliation: Southwest Medical University, First Affiliated Hospital of Sichuan Medical University

#Expression Of CD54 #All Trans Retinoic Acid + Show 8 more

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Abstract

Objective To explore the effect of all trans retinoic acid (ATRA) on the expression of CD106 and CD54 in human bone mesenchymal stem cells and cell growth curve in vitro. Methods The expression of CD54 and CD106 of human BM-MSC was detected by flow cytometry, and cell growth curve of human BM-MSC was tested by MTT assay after coculturing with 0.01, 0.1, 1.0 and 10.0 μmol/l ATRA, respectively. Results The expression of CD54 and CD106 is increased by 0.01, 0.1, 1.0 and 10.0 μmol/1 ATRA in vitro. Conclusion The expression of CD54, and CD106 of human BM-MSC was up-regulated by ATRA. Key words: Tretinoin; Mesenchymal stem cell; Cell adhesion molecule

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