Abstract
Publisher Summary This chapter discusses findings that were obtained during the course of electrocorticographic conditioning in 16 human subjects who were treated with adrenocorticotropic hormone (ACTH) and ACTH fragments. Regarding the effect of corticosteroids on central nervous processes, it was suggested that they facilitate internal inhibition and that such an action is mediated via descending inhibitory influence of the basal forebrain that plays a basic role in the control of sensory input into the diencephalon. The synchronization of electroencephalographic (EEG) activity, or the enhancement of alpha rhythm, is a common phenomenon during differential conditioning as a response to the differential signal and during the course of the extinction of conditioned reflex activity. Both ACTH and corticosteroid treatment resulted in an increased convulsive reactivity, a slowing of the EEG activity, and an increased sensitivity to hyperventilation and photic driving in human subjects. The subjects were hospitalized for reason of minor neurological symptoms during the whole observation period.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
