The present status of ACTH and adrenal steroid therapy in medicine.

Abstract

Article1 October 1955THE PRESENT STATUS OF ACTH AND ADRENAL STEROID THERAPY IN MEDICINEJ. C. BECK, M.D., F.R.C.P.(C)J. C. BECK, M.D., F.R.C.P.(C)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-43-4-667 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptIn this era, with important new medical advances proceeding at such a rapid rate, it is often difficult to afford a new discovery its rightful place. However, the majority would agree that a sense of being on the threshold of a great achievement greeted the announcement of the clinical effects of ACTH and cortisone in rheumatoid arthritis and rheumatic fever by Hench1, 2and his collaborators in 1949. This is particularly true if one recalls the first clinical ACTH Conference, at which time most observers felt that a revision of the present concept of many diseases was necessary. Since these...Bibliography1. HenchKendallSlocumbPolley PSECCHHF: The effect of a hormone of the adrenal cortex (17-hydroxy-11-dehydrocorticosterone: compound E) and of pituitary adrenocorticotropic hormone on rheumatoid arthritis, Proc. Staff Meet., Mayo Clin. 24: 181, 1949. MedlineGoogle Scholar2. HenchSlocumbBarnesSmithPolley PSCHARHLHF: The effects of the adrenal cortical hormone 17-hydroxy-11-dehydrocorticosterone (compound E) on the acute phase of rheumatic fever: preliminary report, Proc. Staff Meet., Mayo Clin. 24: 277, 1949. MedlineGoogle Scholar3. BrowneMcAlpineHoffman JSHTMM: Conference on metabolic aspects of convalescence, 1948, Josiah Macy, Jr. Foundation, New York, pp. 148-158. Google Scholar4. ThornForshamFrawleyHillRocheStaehelinWilson GWPHTFSRMDD: The clinical usefulness of ACTH and cortisone, New England J. Med. 242: 783, 824 and 865, 1950. CrossrefMedlineGoogle Scholar5. AstwoodRabenPayneGrady EBMSRWAB: Purification of corticotropin with oxycellulose, J. Am. Chem. 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BunimPechetBollett JJMMAJ: Studies on metacortandralone and metacortandracin in rheumatoid arthritis—antirheumatic potency, metabolic effects and hormonal properties, presented at the Interim Session of the American Rheumatism Association at the National Institutes of Health, Bethesda, Maryland, November 4, 1954. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Montreal, Canada*From the Symposium on ACTH and Cortisone, presented at the Thirty-sixth Annual Session of The American College of Physicians, Philadelphia, Pennsylvania, April 28, 1955.From the McGill University Clinic, Royal Victoria Hospital, Montreal, Canada. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byManagement of Airway Secretions in Patients with Severe Respiratory Muscle DysfunctionRHEUMATISM AND ARTHRITIS: REVIEW OF AMERICAN AND ENGLISH LITERATURE OF RECENT YEARS (TWELFTH RHEUMATISM REVIEW)* Part IICHARLEY J. SMYTH, M.D., F.A.C.P., JOSEPH J. BUNIM, M.D., F.A.C.P., WILLIAM S. CLARK, M.D., F.A.C.P., DARRELL C. CRAIN, M.D., F.A.C.P., FELIX E. DEMARTINI, M.D., IVAN F. DUFF, M.D., F.A.C.P., EPHRAIM P. ENGLEMAN, M.D., F.A.C.P., DONALD C. GRAHAM, M.D., F.R.C.P. (C), MAX M. MONTGOMERY, M.D., F.A.C.P., BERNARD M. NORCROSS, M.D., F.A.C.P., HOWARD F. POLLEY, MARIAN W. ROPES, M.D., F.A.C.P., EDWARD F. ROSENBERG, M.D., F.A.C.P.Infections Complicating Cortisone TherapyAdvances in Chemotherapy of Cancer in Man 1 October 1955Volume 43, Issue 4Page: 667-684KeywordsAdrenocorticotropic hormoneAsthmaColitisPathogenesisRheumatic feverRheumatoid arthritisSteroid therapyUlcerative colitis Issue Published: 1 October 1955 PDF downloadLoading ...