Abstract
Quantitative data are presented relating to the effects of a series of 3-substituents upon orientation in the formation of ethyl pyrazolo[1,5-a]pyridine-3-carboxylates by a 1,3-dipolar cycloaddition reaction between 3-substituted pyridine N-imides and ethyl propiolate. The observed regioselectivity is discussed in terms of electronic and steric factors as well as hydrogen-bond formation.
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