Abstract
ObjectiveThe objective of this study is to assess effectiveness of directly observed treatment short course (DOTS) in treatment of tuberculosis (TB) patients in all public health facilities of Debre Tabor town, Ethiopia from January 2016 to December 2017.ResultAmong 354 TB patients, 53.1% were males. Furthermore 22.6%, 40.4%, and 37% were smear positive pulmonary, smear negative pulmonary and extra pulmonary TB respectively. Study also revealed that TB–human immunodeficiency virus (HIV) co-infection and overall TB treatment success rate were 18.1% and 90.7% respectively. Regular weigh follow-up, sputum follow-up and HIV status were significantly associated with treatment success with P-value < 0.001, < 0.001 and 0.334 respectively. But TB treatment success weren’t associated with sex (P = 8.62), health facility type (P = 0.749) and TB type (P = 0.778). The study also showed that the overall TB treatment success rate was in line with World Health Organization (WHO) target on treatment success rate. Furthermore the study indicated higher TB–HIV co-infection and variations in conducting regular weight and sputum follow-up among HFs.
Highlights
Tuberculosis (TB), one of the oldest infectious diseases, is causing significant morbidity and mortality all over the world [1]
Among health facilities (HFs) studied, the highest smear positive pulmonary TB patients were identified in Ginbot 20 Health Centers (HCs) followed by Hidar 11 HC with 30.6% and 25.5% respectively (Fig. 1)
The study indicated that 37%, 40.4% and 22.6% of TB patients were diagnosed as having extra pulmonary TB (EPTB), smear negative pulmonary TB (PTB−) and smear positive pulmonary TB (PTB+) respectively
Summary
Tuberculosis (TB), one of the oldest infectious diseases, is causing significant morbidity and mortality all over the world [1]. Based on World Health Organization (WHO) report, there are 10 million cases and 1.6 million deaths globally in 2017 [1]. The impact of tuberculosis is more pronounced in developing than developed world mainly in Africa where. As part of developing country, Ethiopia is highly affected by the impact of tuberculosis. Ethiopia is one of the 22 TB high burden countries. Based on 2016 WHO report, the incidence of TB cases in Ethiopia were 207 per 100,000 population in 2014 [2]. TB is the second cause of death in Ethiopia based on 2009/10 health and health related indicators of the Federal Ministry of Ethiopia [3]
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