Abstract
Effectiveness of Combined Use: Inactivated Vaccines with Immunostimulants on the In vivo Model of Teschen Disease
Highlights
IntroductionThe Teschen disease (enzootic encephalomyelitis, enterovirus encephalomyelitis in pigs) is a viral disease in pigs, characterized by the development of non-suppurative encephalomyelitis and the emergence of paralysis
The Teschen disease is a viral disease in pigs, characterized by the development of non-suppurative encephalomyelitis and the emergence of paralysis
“Navlya” strain, with a titer of 5.5-8.0 lg TCID50/cm3; infectious rhinotracheitis virus (IRT) of cattle, “TK–A” strain, with a titer of 7.0 lg TCID50/cm3 were used from the State collection of microorganisms of Federal Research Center of Virology and Microbiology
Summary
The Teschen disease (enzootic encephalomyelitis, enterovirus encephalomyelitis in pigs) is a viral disease in pigs, characterized by the development of non-suppurative encephalomyelitis and the emergence of paralysis. All age groups of domestic pigs are sensitive to the disease, but in the greater risk zone is the young of pigs (Barinsky et al, 2015; Romantsov et al, 2004). Rarely exceeding 72 hours, low temperature, loss of appetite, sometimes vomiting, acute rhinitis, movement coordination disorder are noted. There are clinical signs of Central nervous system (CNS) lesions: twitching of various muscle groups, involuntary movement, weakness muscles of the limbs, nystagmus, etc. Symptoms destruction spinal brain develop - staggering tense gait, weakness limbs, incomplete their leaning on land, progressive paralysis, gradually seizing
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