Abstract
Dental caries is an infectious disease that can occur in children, sometimes as soon as the teeth eruption starts. Nanotechnology provides effective strategies in prevention and treatment of dental caries. The purpose of this study was to determine the effectiveness of the addition of silver nanoparticles to a fluoride varnish for the remineralization of primary teeth with white spot lesions. A trial was carried out in children with dental demineralization (white spot lesions) on both maxillary dental teeth. One of the teeth received three applications of a fluoride varnish with silver nanoparticles, and the other one, three applications of the same varnish without the silver nanoparticles. We measured the mineral content of the teeth with a laser cavity detection device (DIAGNOdent®) before the first application of the varnishes, and 3 months after the last application. The results show significant differences between teeth treated with silver nanoparticles. Teeth have been treated with fluoride varnish added with silver nanoparticles seemed to enhance dental structure than teeth treated with conventional varnish, and this effect was also found between basal and final measurements in this group. The fluoride varnish added with silver nanoparticles seems to be more effective in the dental remineralization. This strategy may be used as a prophylactic measure to avoid development of caries.
Highlights
Many strategies have been developed for maintenance of the integrity of the enamel structure; the application of fluoride agents in various forms is a proven approach that strengthens the enamel structure [1]
These varnishes are used in the treatment of white spot lesions (WSLs), which indicates dental demineralization; it has been supported that the early diagnosis or detection of WSLs and the use of non-invasive therapies such as fluoride are important strategies for controlling the development of dental caries [5]
The combination of these strategies may confer a better treatment of the WSLs; the purpose of this research was to determine the effectiveness of the addition of AgNPs to a fluoride varnish for the remineralization of white spot lesions, and to know if the fluoride varnish added with silver nanoparticles can be used to improve oral health quality and avoid the development of caries
Summary
Many strategies have been developed for maintenance of the integrity of the enamel structure; the application of fluoride agents in various forms is a proven approach that strengthens the enamel structure [1]. Fluorinated varnishes have been used as preventive methods for caries development both in the general population, and in patients with special needs since they possess the ability to adhere to dental surfaces for relatively long time, and they do not require special application techniques [2,3,4] These varnishes are used in the treatment of white spot lesions (WSLs), which indicates dental demineralization; it has been supported that the early diagnosis or detection of WSLs and the use of non-invasive therapies such as fluoride are important strategies for controlling the development of dental caries [5]. The combination of these strategies may confer a better treatment of the WSLs; the purpose of this research was to determine the effectiveness of the addition of AgNPs to a fluoride varnish for the remineralization of white spot lesions, and to know if the fluoride varnish added with silver nanoparticles can be used to improve oral health quality and avoid the development of caries
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