Abstract

Most of mood stabilizers and antipsychotic agents are commonly used for early-onset bipolar disorder in clinical settings although there is limited number of randomized controlled trials with youths. Also, there are few prospective studies for the treatment of depressive episodes in bipolar disorder and maintenance therapy in children and adolescents. Here we report a 16 years-old adolescent with rapid cycling bipolar disorder who responded well to olanzapine monotherapy both at the acute manic phase and during the maintenance treatment. Olanzapine seems to be an effective choice during both acute phase and maintenance treatment of bipolar disorder in adolescents. Also, improvement in manic symptoms appears in the early days of treatment.

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