Effect of Yoga and Traditional Physical Exercise on Hormones and Percentage Insulin Binding Receptor in Patients with Type 2 Diabetes

Eslaen Martorell Zamoraz,David Garwood,Donovan Mcgrowder,Errol York Morrison,Rachael Irving,Ruby Alexander-,Lorenzo Gordon,Yeiny Fraser Penas

doi:10.3844/ajbbsp.2008.35.42

Eslaen Martorell Zamoraz, David Garwood + Show 6 more

Open Access

https://doi.org/10.3844/ajbbsp.2008.35.42

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Abstract

The objective of the study was to investigate the short-term impact of a brief lifestyle intervention of yoga and traditional Physical Training (PT) exercise regimens on: serum insulin, percentage insulin binding receptor, internalization of insulin-receptor complex, T3, T4, TSH and cortisol at baseline, 3 months and 6 months in patients with type 2 diabetes mellitus. A total of 231 patients completed this prospective randomized study with 77 type 2 diabetic patients in the yoga group (62 females and 15 males) that were matched with the same number of patients in the traditional Physical Training (PT) exercise and control groups. Biochemical parameters such as fasting Blood Glucose (FBG), serum insulin, percentage insulin binding receptor and internalization of insulin-receptor complex were determined at the beginning (baseline) and two consecutive three monthly intervals. The effect of the lifestyle interventions on hormones such as cortisol, TSH, T4 and T3 were also investigated. The FBG concentration in the yoga and the traditional PT exercise groups were markedly decreased compared with control (P 0.05). The findings indicates the beneficial effects of yoga and traditional PT exercise regimens in improving glycaemic control by increasing percentage insulin binding receptor in type 2 diabetic patients with no significant change in cortisol and thyroid hormones.

Highlights

Individuals with type 2 diabetes and poor glycaemic increases the rate of glucose uptake into the contracting control may develop severe microvascular skeletal muscles, a process that is regulated by the Corresponding Author: Dr Lorenzo Gordon, Department of Medicine, University of the West Indies, Kingston 7, Jamaica W.I
This study evaluated the effects of yoga and traditional physical training (PT) exercise regimens on fasting blood glucose, serum insulin, percentage insulin binding receptor and internalization of insulin-receptor complex at baseline, 3 months and 6 months in individuals with type 2 diabetes mellitus
A total of 231 subjects were recruited for this prospective randomized study: 77 type 2 diabetic patients in the yoga group (62 females and 15 males) that were matched with 77 type 2 diabetic patients in the traditional PT exercise group (62 females and 15 males) and another 77 type 2 diabetic patients serving as the control group (62 females and 15 males)

Summary

Introduction

There is a profound relationship among the thyroid, adrenal and pituitary glands in the initiation and progress of diabetes mellitus and there are several interconnecting points amongst them These relationships can determine many alterations, including the changes in the degree of glucose tolerance, which represent a risk factor for cardiovascular diseases (CVD), type 2 diabetes mellitus and stroke[14]. Yoga is an ancient Indian science and a number of controlled studies exist on the effectiveness of yoga These investigations include such conditions as cardiovascular disease[15,16] and diabetes mellitus[17]. This study evaluated the effects of yoga and traditional physical training (PT) exercise regimens on fasting blood glucose, serum insulin, percentage insulin binding receptor and internalization of insulin-receptor complex at baseline, 3 months and 6 months in individuals with type 2 diabetes mellitus. In addition we evaluated the effect of these two exercise regimens on cortisol, TSH, T4 and T3 in the same time period

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