Abstract
In this study, the effect of vitamin B3 supplement given to rats was investigated on glutathione redox cycle by looking at glutathione peroxidase and glutathione s transferase activities. 20 Wistar albino male rats were used. Vitamin B3 supplement was given to one of the two groups that were formed. The other group was determined as the control group. 360 mg/kg/day vitamin B3 supplement was given by oral gavage method for 10 days. At the end of 10 days, intracardiac blood samples were taken. Glutathione peroxidase activity level was determined as 1033.44±198.05 U/L in the vitamin B3 supplement group and 526.00±99.54 U/L in the control group. The glutathione peroxidase activity level of the vitamin B3 supplemented group was found to be statistically significantly higher than the glutathione peroxidase activity level of the control group (p
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