EFFECT OF TRANSCUTANEOUS IRRADIATION UNDER THE RADIAL ARTERY ON HEMODYNAMIC VARIABLES OF HYPERTENSIVE PATIENTS: DOUBLE BLIND CLINICAL STUDY

Abstract

Systemic arterial hypertension (SAH) is a multifactorial clinical condition with a high morbidity and mortality rate and low control rates. Although photobiomodulation (PBM) is capable of inducing a photobiological interaction within cells and modifying the micro and macrovascular response in situ, there is a lack of studies demonstrating its systemic effect, especially clinical and placebo-controlled studies. Thus, this study aimed to evaluate the modulatory effects on blood pressure control in hypertensive patients after transcutaneous photobiomodulation of the radial artery. For this purpose, 44 participants were randomly divided into 4 groups, one group irradiated for 60 minutes daily for 5 days, repeating after 20 days with a total of 3 cycles (Group A), and its respective placebo (Group B); The third group was irradiated for 30 minutes daily for 10 days, repeating after 20 days, also totaling 3 cycles (Group C), and its respective placebo (Group D). All participants remained with conventional drug treatment previously instituted. Before the interventions, after each cycle and at the end of them, blood pressure and heart rate were measured. Before and at the end of the interventions, blood samples were collected to measure interleukins 6 and 1beta. Statistical analysis was performed to compare the groups in each phase of the treatment, with α = 0.05. Modulatory effects were evidenced in the control of blood pressure in hypertensive patients after photobiomodulation. Group A showed a better response to the reduction of hemodynamic variables than group C. Multidisciplinary care may have increased adherence to treatment of all participants, including the placebo groups, which also showed a decrease in the values ​​of hemodynamic variables.