Abstract
This study assessed the influence of transcutaneous electrical acupoint stimulation (TEAS) combined with transversus abdominis plane block (TAPB) on the recovery of elderly patients undergoing laparoscopic gastric cancer surgery. Ninety patients (age ≥ 60years) undergoing laparoscopic gastric cancer surgery were randomly divided into general anesthesia group (groupG), TAPB group (groupNG), and TEAS combined with TAPB group (groupNTG). Patients in the NTG group received TEAS at PC6, LI4, and ST36 acupoints and TAPB. Patients in the NG group received TAPB. The quality of recovery (QoR) was assessed using the QoR-15 questionnaire. The percentages of Tlymphocyte subsets were determined. Consumption of anesthetics, extubation time, visual analog scale (VAS) scores, time of first postoperative ambulation and flatus, and postoperative adverse events were also recorded. QoR-15 scores on postoperative day (POD) 3 and POD7 were higher in the NTG group than in the G and NG groups (P < 0.05). On POD1 and POD3, the percentages of CD3+ and CD4+ Tcells and the CD4+/CD8+ ratio were higher and the percentage of CD8+ Tcells was lower in the NTG group than in the G and NG groups (P < 0.05). Remifentanil consumption, and the incidence of postoperative nausea and vomiting (PONV) were lower and extubation time and time of first postoperative flatus were shorter in the NTG group than in the G and NG groups (P < 0.05). Compared with the G group, the VAS scores on POD1 were lower in the NG group and those on POD2 were lower in the NTG group (P < 0.05). The combination of TEAS and TAPB ameliorated postoperative pain, improved immune and gastrointestinal function, reduced the incidence of PONV, and effectively promoted postoperative recovery in elderly patients undergoing laparoscopic gastric cancer surgery. Chinese Clinical Trial Registry (ChiCTR2100042119).
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