Abstract
Extract: Triodothyronine (T3) was given daily by injection to rats from 1 day of age to 2 hr prior to death. In the brain microsomal fraction of 5− to 6-day-old animals, incorporation of malonyl-CoA into total fatty acids increased from 0.9 to 2.25 mμmoles/mg protein. Although thyroid increased precursor incorporation into total fatty acids in other age groups, the difference was not statistically significant. Increased precursor incorporation was entirely due to increased formation of saturated fatty acids, and this effect was observed at all age groups.
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