Abstract
Objective To investigate the relationship between thrombus-aspiration and platelet activating factor (PAF) during emergency percutaneous coronary intervention(PCI) in patients with acute ST segment elevation myocardial infarction(STEMI).Methods One hundred STEMI patients underwent emergent PCI from June 2009 to September 2011 were choosed,50 patients received thrombus aspiration were enrolled in study group,and 50 patients who only received routine PCI were enrolled in control group.The clinical data and the PAF levels were compared between the two groups.Results The PAF levels increased after PCI in both groups (P ＜ 0.05).Compared with control group,patients in thrombus aspiration group had lower serum PAF level; The level of serum PAF was higher in the patients complicated with thrombus burden.Conclusions Thrombus-aspiration can lower the level of PAF,decrease the platelet aggregation and activation in micro-vascular vessel and improve myocardium blood perfusion in infarction area during emergency PCI in patients with STEMI. Key words: ST segment elevation myocardial infarction; Thrombus-aspiration; Platelet activating factor
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
