Abstract

Recent advances in the staging of musculoskeletal sarcomas, improvements in diagnostic imaging, and the use of preoperative chemotherapy have enabled the orthopedic oncologist to offer limb salvage surgery to an increasingly larger number of patients as an alternative to amputation. The reconstruction of large osseous defects following the resection of malignant tumors is difficult, not only because of the size of the defect but also because of the unpredictable incorporation of bone grafts following chemotherapy or irradiation. The reconstruction of bone defects has recently been facilitated with the use of custom-made porous coated segmental defect replacement (SDR) prostheses [1–3]. In order to obtain the optimal fixation of segmental defect replacement (SDR) prostheses, the concept of extracortical bone bridging and ingrowth was advocated as it has been shown to be effective in both animal models and clinical studies [4–8].

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