Abstract
The effect of Bisolbi drug based on Bacillus subtilis on the physiological, biochemical and productive parameters of calves was studied. The research and production experiment was carried out in a dairy farm “Kupinskoe” of Samara Region on 30 calves of the Holstein-Frisian breed. The drug increases the intensity of the anabolic processes in animals: the amount of total protein in blood serum of calves of the experimental group at 120 days of age was higher by 8.9% (p≤0.05), albumin 9.2% (p≤0.01), compared with control animals. The purpose of Bisolbi contributed to the increase in the intensity of carbohydrate-lipid metabolism: cholesterol was higher by 23% (p≤0.01), glucose 0.4 mmol/l (p≤0.05) in blood 120-day calves of the experimental group, relative to the data of the control group. It was found that the body weight of calves in the control group at 100 days of age was 105.23±2.11 kg, in the experimental group -108.6±2.19 kg. The average daily gain in the experimental group was significantly higher by 0.075 kg (p≤0.01). At 120 days of age, the body weight of the experimental calves was higher by 4.19 kg (p≤0.05), the average daily increase by 0.080 kg (p≤0.05), relative to the control animals.
Highlights
Rearing of young animals is one of the most important technological processes in animal husbandry
The scientists have proven that the use of mineral adsorbents, probiotics and other biologically active substances in addition to the main diet leads to an increase in the metabolism in the body of farm animals, an increase in the absorption of nutrients and a decrease in feed costs per unit of body weight gain [1,2,3,4,5,6]
Due to its highly efficient protein secretion system and adaptable metabolism, Bacillus subtilis microbial cells are widely used for the production of recombinant proteins, especially those associated with the production of chemicals, enzymes, and antimicrobial materials for the food industry, agriculture, and medicine [7,8,9]
Summary
Rearing of young animals is one of the most important technological processes in animal husbandry. The use of probiotics in the diets of young farm animals during the intensification of the industry is necessary, since the optimal ratio of the microflora of the digestive tract is disturbed by changing the type of nutrition, rearrangement of the herd, high concentration of livestock per unit area, treatment with antibiotics and sulfonamide drugs. The scientists have proven that the use of mineral adsorbents, probiotics and other biologically active substances in addition to the main diet leads to an increase in the metabolism in the body of farm animals, an increase in the absorption of nutrients and a decrease in feed costs per unit of body weight gain [1,2,3,4,5,6]. Due to its highly efficient protein secretion system and adaptable metabolism, Bacillus subtilis microbial cells are widely used for the production of recombinant proteins, especially those associated with the production of chemicals, enzymes, and antimicrobial materials for the food industry, agriculture, and medicine [7,8,9]
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