Effect of systematic nursing intervention on cancer-related fatigue in advanced non-small cell lung ;cancer patients undergoing chemotherapy

Abstract

Objective To explore the effect of systematic nursing intervention on cancer-related fatigue （ CRF） in advanced non-small cell lung cancer （ NSCLC） patients undergoing chemotherapy .Methods Eighty advanced NSCLC patients undergoing chemotherapy were divided into the intervention group and the control group according to the random number table , each with 40 cases.The control group received the routine nursing according to the doctor ’ s advice for tumor patients , and the intervention group received the systematic CRF nursing intervention on the basis of the control group .The CRF and life quality of patients were evaluated by the Brief Fatigue Inventory （ BFI） and the Functional Assessment of Cancer Treatment-Lung （ V3.0） （ FACT-L） before and 15 d after the intervention between the two groups .Results Eighty questionnaires were issued and 80 questionnaires were responsive with an effective response rate of 100%.No difference was found in the degree of fatigue before the intervention between the two groups （P>0.05）.The degree of CRF in the intervention group was significantly lower than that in the control group after the intervention , and the difference was statistically significant （χ2 =8.47, P=0.04）.The scores of physiological status , social/family status, relationships with physicians , emotional state , functional status , additional attention and total score of scale were respectively （32.15 ±6.08）, （35.31 ±5.33）, （12.38 ±2.67）, （28.59 ±4.53）, （34.34 ±5.86）, （43.80 ±7.76）, （186.57 ±32.23）in the intervention group, and were （25.45 ±5.42）, （28.68 ±4.16）, （9.95 ±1.49）, （21.87 ±3.95）, （26.21 ±5.01）, （36.63 ±8.24）, （148.79 ±28.27） in the control group, and the differences were statistically significant （t=5.20, 6.20, 5.03, 7.07, 6.67, 4.01, 5.57, respectively; P<0.01）.Conclusions The systematic nursing intervention based on routine nursing can alleviate the degree of CRF in advanced NSCLC patients with chemotherapy , and improve the life qualify of patients . Key words: Non-small cell lung cancer,advanced; Cancer-related fatigue; Nursing intervention