Abstract
The 82Sr/82Rb generator is used to produce a medical radiopharmaceutical rubidium-82 chloride in saline solution for PET investigation. In this work, we studied the effect of the amount of stable strontium and calcium delivered to the sorbent (hydrated tin dioxide), on the maximum volume of radiopharmaceutical solution that can be obtained from the generator. Sr and Ca may be delivered to the sorbent from the initial solution of strontium-82 or from the eluent (0.9% NaCl) during medical application of the generator. It is shown that this volume depends on the value CSr + 0.11CCa, where CSr and CCa - molar concentrations of the elements in 1 g of the sorbent. The obtained results make it possible to increase significantly the productivity and reliability of the used generators.
Published Version
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