Abstract
Effect of Smoking on Ocular Surface and Tear Film: A Clinico Pathological Study
Highlights
Tobacco smoking is a serious public health problem which contains various heavy metals and toxic mineral elements that has been associated with cardiovascular and respiratory disorders
The mean age of the smoker 35.5 years ± 7.64 years and the mean age of non smokers in control group was 33.60 ± 5.54 years Mean tear film break up time in non smoker was 14.71 ± 4.34 sec as compared to 11.25 ± 2.29 seconds in smokers (p=0.0001)
20% of the subjects in smoker group shows grade 2 metaplasia and 8 % showed grade 3 metaplasia in comparison to 2% and 0 % in non smoker group respectively (p=0.0001)
Summary
Tobacco smoking is a serious public health problem which contains various heavy metals and toxic mineral elements that has been associated with cardiovascular and respiratory disorders. Tobacco smoke contain more than 4000 compounds and a puff of smoke contain 300 million to 3.5 billion particles existing either in gas or particulate form which on exposure are eventually toxic to ocular tissue and affect eye through ischemic and oxidative mechanism [1]. Tobacco smoking is associated with cataract [2], ARMD [3], AION and toxic optic neuropathy and with dry eye syndrome. Ocular surface is highly sensitive to air borne chemical fumes and irritative gas and its persistent exposure may lead to ocular surface damage and dry eye syndrome. Environment, lifestyle, age, sex, drug history, and systemic diseases are the major risk factor associated with dry eyes, among which the lifestyle factors may play an important role [4].
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