Abstract
Objective To Observe the levels of TNF,IL-6,IL-8 in patients with pulmonary contusion before and after treatment,explore its effect on the treatment of pulmonary contusion.Methods 110 pulmonary contusion patients were selected from wendeng central hospital thoracic surtcal ward,110 patients were randomly divided into treatment group and control group.The control group received routine treatment.tIle treatment group on the basis of conventional therapy was added Shenfu injection.The levels of TNF,IL-6,IL-8 from patients were tested.Results The two groups gcore showed no significant difference before treatment(P>0.05).Plasma TNF,IL-6,IL-8 levels in the treatnent group significantly reduced compared with control group after treatment(P<0.051.Conclusion Shenfu injection has therapeutic effect on pulmonary contusion,itcan reduce TNF,IL-6,IL-8 levels,antagonize TNF,IL-6,IL-8 of the vasoconstrictive effect,thereby reducing TNF,IL-6,IL-8 caused secondary lung injury,promote the repair of damaged tissue and lung function recovery. Key words: Pulmonary contusion; Shenfu injection; Tumor necrosis factor; Interleukin
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