Effect of serum lipid subfractions on nuclear magnetic resonance spectroscopy's ability to detect coronary atherosclerosis early

Abstract

Nuclear magnetic resonance spectroscopy, also known as NMRS, is a cutting-edge method based on nuclear magnetic induction theory and quantum optics that has found extensive usage in the domains of chemical analysis, life science, and other disciplines. The method is quantitative and repeatable, making it particularly effective for detecting and analyzing tiny compounds in complicated solutions like blood and urine. With a high degree of standardization and automation, it can assess 114 hemo lipoprotein subfractions and particles in human serum/plasma in a targeted way (exact quantification) and produce precise and dependable detection findings. All processes may be tracked back to fulfill our requirements for non-targeted analysis, which is suited for biological fluid specimens and water-soluble specimens from tissue or cell extracts. The 114 lipoprotein subfractions and particles can be targeted using nuclear magnetic resonance spectroscopy (NMRS), which can detect the serum lipid profile in its entirety. The analysis of the serum lipid profile, the correlation between the levels of lipid subfractions and lipid particles and the degree of coronary stenosis, and the development of a coronary stenosis early warning system can therefore improve the current risk model on the inadequacy of the risk stratification of the patients. These studies are based on a cohort of individuals with varying degrees of coronary atherosclerosis. The development of a coronary artery stenosis early warning system might enhance the patient risk classification models already in use. To analyze the correlation of lipid subfractions and particle levels with cardiovascular events and therapeutic efficacy, to explore more effective biomarkers for lipid-lowering monitoring, and to evaluate the efficacy of classical Chinese medicinal preparations.