Abstract

The histochemical activities of succinic dehydrogenase and cholinesterase in mouse tissues after administration of scorpion ( Buthus minax ) venom have been studied. There were obvious changes in the enzyme activities, of the chronically treated animals, in the kidney, heart and liver. The decreases in cholinesterase activity were greatest in the white matter of the brain, in the portal tract and in some liver cells, while the spleen showed increased activity. A decrease in succinic dehydrogenase activity was observed in the kidney, heart, and liver of the chronically treated mice, while the spleen showed no change in the activity. The striated muscles of the acutely treated mice were fragmented and vacuolated with a loss of their striation. The intramuscular nerve axons became beaded and the subneural apparatus and their terminal expansions were smaller.

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