Effect of saw palmetto extrac on bleeding volume in transurethral plasmakinetics resection of prostate

Abstract

Objective To observe the effect of perioperative use of saw palmetto extrac(SPE) on the bleeding volume in transurethral plasmakinetics resection of prostate(TUPKRP). Methods A total of 150 patients with benign prostate hyperplasia(BPH) were randomly divided into SPE group, finasteride group and control group. Patients in SPE group had taken SPE 160 mg orally once a day for 4 weeks before operation and 1 week after operation. Patients in finasteride group had taken finasteride 0.5 mg orally once a day for 4 weeks before operation and 1 week after operation. None of 50 patients in the control group had taken any drugs. All patients underwent transurethral plasmakinetics resection of prostate by the same surgical team. The operation time, postoperative hemoglobin decrease, postoperative hematocrit decrease and postoperative bladder lavage fluid volume were compared and analyzed among the 3 groups. Results All operations were successful, and none patients treated with SPE and finasteride reported any side effects. The operation time, postoperative hemoglobin decrease, postoperative hematocrit decrease and postoperative bladder lavage fluid volume of SPE group and finasteride group were evidently lower than control group (P 0.05). Conclusions SPE can reduce postoperative blood loss, the bladder lavage fluid volume, and short the operation time in BPH patients underwent TUPKRP. It is worthy of popularization. Key words: Prostatic Hyperplasia; Transurethral Resection of Prostate; Electrosurgery; Hemorrhage; Serenoa