Abstract

Objective To investigate the effect of rosuvastatin calcium on lipids and inflammatory factors C-reactive protein in patients with unstable angina.Methods Totally seventy patients with unstable angina were chosen in the study.The patients were randomly divided into two groups:the control group (n =35) and the therapeutic group(n =35).The patients in control group were treated by routine therapy with nitrates,β-blockers,ACEI and antibloodplatelet therapy.The patients in therapeutic group were treated with rosuvastatin calcium on the basis of routine therapy.The levels of C-reactive protein and lipids were measured before and after treatment in both groups.Results After treatment,the level of Creactive protein and lipids decreased.And the therapeutic group decreased more than the control group,the difference was statistically significant (P ＜ 0.05).Conclusions Rosuvastatin calcium in treatment of unstable angina can not only reduce cholesterol,but also reduce the inflammatory response,so it is conducive to atherosclerosis plaque stability. Key words: Rosuvastatin calcium ; Unstable angina; Lipids ; C-reactive protein

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