Abstract
Objective To evaluate the right ventricular function by Tei index,and investigate the influence of preoperative right heart function on the clinical efficacy of patients with cardiac resynchronization therapy(CRT).Methods Twenty-six CRT recipients with chronic heart failure were studied,each patient received standard echocardiographic examination and cardiac function evaluation before CRT and in the follow-up.At 6 months after CRT,group A(the responder to CRT) was defined as the patients with a decrease of NYHA ≥ 1 and a decrease of left ventricular end-systolic volume (LVESV) ≥15％ at least,while the others were defined as group B(no-responder to CRT).The echocardiographic parameters of right ventricular Tei index and conventional parameters were statistically analyzed.Results There were 18 cases in group A and 8 cases in group B.Compared with group B,the Tei index in group A before CRT was remarkable lower than that in group B[(0.44 ±0.07)vs.(0.55 ±0.07),P ＜0.05],PAP in group A also was remarkable lower than group B [(39 ± 9) mm Hg vs.(50 ± 7) mm Hg,P ＜ 0.05].At 6 months after CRT,in the group A:the Tei index dereased remarkably [(0.44 ± 0.07)vs.(0.39±0.08),P ＜ 0.05],PAP also decreased [(39 ±9)mm Hg vs.(35 ±7)mm Hg,P ＜0.05].In the group B:the Tei index increased remarkably [(0.55 ± 0.07) vs.(0.68 ± 0.08),P ＜0.05],whereas the level of PAP had no remarkably change.Conclusions Preoperative right ventricular function can affect cardic resynchronization therapy effect.Routine assessment of right ventricular should be considered in the evaluation of patients for CRT. Key words: Chronic heart failure; Cardic resynchronization therapy; Right ventricular myocardial performance index; Pulmonary artery pressure
Published Version
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