Abstract
Many people have the opinion that the use of herbal medicines that are used together with chemical drugs is considered safe and does not cause side effects that are harmful to health. In general, all diseases can cause pain. The state of pain is a sensory and emotional event that is uncomfortable to feel due to tissue damage. Plants from nature that are often used for analgesic therapy are guava plants, tropical plants from the Myrtaceae family. This study aimed to determine the activity of red guava leaf extract (Psidium guajava L.) and its combination against paracetamol tablet analgesics in white male mice (Mus musculus). This research method is an in vivo experimental method which consists of making red guava leaf simplicia, red guava leaf extraction, phytochemical screening, and analgesic activity test. The results of this study were red guava leaf extract with a dose of 200 mg/kgBW was able to provide a pain barrier of 49.59% and red guava leaf extract combined with paracetamol at a dose of 65 mg/kgBW gave a pain barrier of 76.42%.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Pharmaceutical Sciences and Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
