Abstract

Precocious development of immature male fowl has been induced by injection of extracts from the anterior lobe of the pituitary1, 2 and by pregnant mare's serum.3 Less marked response of the ovary, oviduct and head furnishings to extracts of the anterior pituitary has been obtained in the immature female fowl1 while oestrin induces precocious development of the oviduct only.4 In the immature pigeon both the testes and ovary responded to injections of pregnant mare's serum, the increase in the weight of the ovary being less than that of the testes.5 The effect of pregnant mare's serum on the immature female fowl has not been reported.For the experiments here reported pregnant mare's serum containing 50 rat units per cc. (obtained from Dr. H. H. Cole) and oestrin containing 1,000 rat units per cc. prepared by the method of Leonard, Hisaw and Fevold6 from pregnant mare's urine, were used. The birds were injected daily for the duration of the experimental periods.In a series of experiments immature white Legho...

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